Grape seed extract attenuates hyperglycaemia-induced in rats by streptozotocin
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Grape seed extract attenuates arsenic-induced nephrotoxicity in rats
Oxidative stress is a recognized factor in nephrotoxicity induced by chronic exposure to inorganic arsenic (As). Grape seed extract (GSE) possesses antioxidant properties. The present study was designed to evaluate the beneficial effects of GSE against arsenic-induced renal injury. Healthy, male Sprague-Dawley rats were exposed to As in drinking water (30 ppm) with or without GSE (100 mg/kg) fo...
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* To whom all correspondence should be addressed. E-mail: [email protected] Diabetes mellitus the most common endocrine disorder of carbohydrate metabolism is affecting approximately 8.3% of the population worldwide (IDF Diabetes Atlas, 2013). In 1675 Thomas Willis added the word ‘mellitus’ to the disease , a word from Latin meaning ‘Honey’ a reference to the sweet taste of the urine (Chopra R...
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Liver injury was induced in female rats using tamoxifen (TAM). Grape seeds (Vitis vinifera) extract (GSE), black seed (Nigella sativa) extract (NSE), curcumin (CUR) or silymarin (SYL) were orally administered to TAM-intoxicated rats. Liver histopathology of TAM-intoxicated:rats showed pathological changes. TAM-intoxication elicited declines in liver antioxidant enzymes levels (glutathione perox...
متن کاملEffects of grape seed extract on oxidative stress and antioxidant defense markers in streptozotocin-induced diabetic rats.
BACKGROUND/AIM To evaluate the effects of grape seed extract (GSE) supplementation on oxidative stress and antioxidant markers in streptozotocin (STZ)-induced diabetic rats. MATERIALS AND METHODS Thirty-six male rats were divided into the following four groups: control, GSE-supplemented control, diabetic, and GSE-supplemented diabetic. Beginning on day 7 after STZ injection, the rats were adm...
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Background: It has been proposed that oxidative stress may contribute to the development of testicular abnormalities in diabetes. Morus alba leaf extract (MAE) has hypoglycemic and antioxidant properties. We, therefore, explored the impact of the administration of MAE on steroidogenesis in diabetic rats. Methods: To address this hypothesis, we measured the serum level of glucose, insulin, and f...
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ژورنال
عنوان ژورنال: Bulletin of Faculty of Pharmacy, Cairo University
سال: 2013
ISSN: 1110-0931
DOI: 10.1016/j.bfopcu.2013.05.003